genetic risk

July 17, 2023

Alzheimer’s genetic risk tracked across sex, race

A Vanderbilt study of genetic risks for cognitive impairment later in life uses data from 32,426 research participants ages 60 and older to elaborate these risks across sex and across the intersection of sex and race.

By Paul Govern
April 20, 2023

Genetics and chronic pain

Polygenic risk scores — scores that reflect the influence of common genetic variants — could be used to predict the likelihood of developing chronic overlapping pain conditions and guide biomarker and targeted prevention efforts.

By Bill Snyder
November 8, 2022

Alzheimer’s risk factor and cognition

Vanderbilt researchers found that a protein with roles in innate immunity worsens memory at baseline in carriers of APOE-e4, the strongest genetic risk factor for Alzheimer’s disease, further implicating neuroinflammation in cognitive decline.

By Leigh MacMillan
June 14, 2018

Shared genetics may shape treatment options for certain brain disorders

Symptoms of schizophrenia and bipolar disorder, including psychosis, depression and manic behavior, have both shared and distinguishing genetic factors, an international consortium led by researchers from Vanderbilt University and Virginia Commonwealth University is reporting.

By Bill Snyder
March 27, 2014

Study links stem cell gene to prostate cancer susceptibility

A gene on chromosome 8 — in a region of the genome linked to risk for many types of cancer — is particularly associated with prostate cancer susceptibility, Vanderbilt University researchers have found.

By Leigh MacMillan
February 28, 2013

Potent genetic risk factor for breast cancer identified

Researchers at Vanderbilt University have found a powerful new genetic risk factor for breast cancer.

By Bill Snyder
October 11, 2012

Amish aid search for Alzheimer’s genes

An analysis of Amish populations revealed novel risk genes for late-onset Alzheimer disease.
By Leigh MacMillan