heart disease

Former heart patient inspired to create Discovery Science Fund

Two vastly different causes of heart failure, both of which can devastate a patient’s life, are being studied at Vanderbilt University Medical Center thanks, in part, to the generosity of a grateful patient whose own damaged heart was repaired at Vanderbilt more than five years ago.

Boosting cell-based heart repair

A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells.

Does fish oil help prevent A-fib?

Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility.

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Atrial disease and hypertension links

New findings suggest that misfolded proteins accumulate in the heart atria, particularly in patients with hypertension, and may contribute to atrial heart disease.

Cholesterol

Major grant spurs deeper look into ‘good cholesterol’

In some cases, HDL, the “good cholesterol,” may not function properly and may actually accelerate atherosclerosis.

Heart illustration

Study finds coronary arteries hold heart-regenerating cells

Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.

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