Helicobacter pylori Archive — Page 1 of 2

Illustration of several teal, curved rod-shaped bacteria with hairlike structures and flagella against a pink-red background.
November 16, 2023

Nasty microbe H. pylori has Achilles’ heel

Vanderbilt researchers found that an H. pylori enzyme is essential for colonization of the stomach, suggesting it as a promising therapeutic target for H. pylori infection.

Medical illustration of a human torso showing the trachea, branching airways, and both lungs, with several clustered blue nodules depicted inside the lungs.
August 1, 2022

H. pylori and lung cancer

Specific biomarkers for H. pylori — a bacterium that infects the stomach — were associated with increased risk of lung cancer, Vanderbilt researchers have discovered.

Medical illustration of the stomach and intestines, with the stomach highlighted in red and an enlarged bacterium-like form shown inside it.
January 17, 2022

H. pylori, lipid loss and stomach cancer

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.

Portrait of Shailja Shah, MD, with long dark hair, wearing a dark top and smiling against a neutral brown background.
August 4, 2021

Study finds genetic factor undermines H. pylori treatment

Helicobacter pylori, a stomach-dwelling bacterium, is a strong risk factor for gastric cancer, peptic ulcers and other debilitating gastrointestinal disorders. Yet efforts to eradicate it using a combination of antibiotics and proton pump inhibitors (PPIs), which suppress gastric acid production, often fail.

x-ray of stomach
October 15, 2020

Factor involved in stomach injury response identified

Researchers at Vanderbilt University Medical Center have identified a key factor that coordinates the body’s repair response to severe injury in the stomach caused, most commonly, by infection by the bacterium Helicobacter pylori.

Medical illustration of the stomach and intestines, with the stomach highlighted in red and an enlarged bacterium-like form shown inside it.
July 23, 2020

Stomach bug hit-and-run

The H. pylori machinery that “injects” an oncoprotein into stomach cells contributes to the development of gastric cancer, Vanderbilt researchers demonstrate.