Huntington's disease

September 7, 2023

Low-flow cerebrospinal fluid in Huntington’s disease: study

Vanderbilt researchers found reduced net flow of cerebrospinal fluid in Huntington’s disease, which could contribute to mutant protein retention and altered responsiveness to medications delivered via the spinal cord.

By Paul Govern
January 6, 2023

Early effects of Huntington disease

Impairments in brain executive function happen earlier than motor symptoms in people with the gene mutation that causes Huntington disease, suggesting younger ages and cognitive symptoms be considered for any future clinical trials.

By Kelsey Pinckard
silhouette of three men with guns
October 5, 2021

Breaking bad with Huntington’s disease

Illegal activities are a significant clinical problem in individuals with Huntington’s disease, highlighting the need for improved screening measures and protocols to guide patient management.

By Paul Govern
August 24, 2017

Huntington’s Disease Clinic lands Level 1 designation

The Vanderbilt University Medical Center (VUMC) Huntington’s Disease Clinic is one of only four in the nation to receive a Level 1 Center of Excellence designation.

By Tom Wilemon
disabled man plays with his daughter
October 29, 2015

Compound developed at VUMC may delay Huntington’s disease

A compound developed by researchers at Vanderbilt University can improve early symptoms and delay progression of Huntington’s disease in a mouse model of the neurodegenerative disorder.

By Bill Snyder
February 26, 2015

VUMC’s Huntington’s Disease Clinic recognized

Vanderbilt University Medical Center’s Huntington’s Disease Clinic has been named a 2015 Center of Excellence by the Huntington’s Disease Society of America (HDSA).

By VUMC News and Communications
November 26, 2014

New tools to probe manganese biology

Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.
By Leigh MacMillan
November 21, 2013

Clinic helps patients cope with Huntington’s disease

Melissa Darnall could easily look around her family reunions and pick out who had Huntington’s disease (HD). The genetic disorder had affected four of her five aunts and uncles and her father, and the balance problems and shakiness typical of HD were readily apparent in those siblings.
By VUMC News and Communications