imaging mass spectrometry

June 2, 2022

Bacterial battle in 3D

Using imaging mass spectrometry and microscopy, Vanderbilt researchers visualized how staph bacteria modifies lipids in its membrane to evade immune system-mediated killing.

By Bill Snyder
January 17, 2022

H. pylori, lipid loss and stomach cancer

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.

By Leigh MacMillan
September 30, 2021

Molecular imaging of C. diff infection

C. difficile — the leading cause of hospital-associated intestinal infections — induces a rapid influx of bile acids into the gut, which could provide a novel target for blocking infection.

By Leigh MacMillan
October 31, 2019

Imaging host-pathogen battle for metal

An unprecedented view of bacterial products within infected tissues opens new opportunities to explore infection biology and devise novel therapeutic strategies.

By Leigh MacMillan
July 11, 2019

New look at atherosclerosis

A new imaging method makes it possible to directly measure cell division and changes in metabolism in atherosclerotic plaques.

By Sanjay Mishra
March 28, 2018

What protein is that?

An improved technology enables high-throughput protein identification in imaging mass spectrometry, aiding proteomics research.

By Leigh MacMillan
September 16, 2013

Mapping brain membrane proteins

New mass spectrometry imaging methods will enable studies of the distribution and identification of membrane proteins directly within tissues.
By Leigh MacMillan
August 9, 2012

Team creates new view of body’s infection response

A new 3-D view of the body’s response to infection — and the ability to identify proteins involved in the response — could point to novel biomarkers and therapeutic agents for infectious diseases.
By Leigh MacMillan