Understanding the roles of various immune cells that reside in the gut lining could shed light on inflammatory bowel diseases.

Louise Rollins-Smith and colleagues are exploring how a deadly fungus counters the amphibian immune response and contributes to declining worldwide amphibian populations.

Mark Boothby and colleagues are exploring the factors that contribute to antibody production and quality, which are key to our defense against pathogens and response to vaccines.

Vanderbilt researchers led by Eric Skaar are probing the mechanisms bacteria use when faced with nutrient starvation — a host defense strategy called “nutritional immunity.”

Using sophisticated gene sequencing and computing techniques, researchers at Vanderbilt University Medical Center and the San Diego Supercomputer Center have achieved a first-of-its-kind glimpse into how the body’s immune system gears up to fight off infection.

A compound that activates a virus-sensing receptor has potent therapeutic effects in a mouse model of breast cancer.

John Karijolich and colleagues have discovered a link between cellular RNA processing and the innate cellular immune response to viral pathogens.