Juvenile Diabetes Research Foundation

Saunders receives diabetes research innovation award

Vanderbilt’s Diane Saunders, PhD, has been selected as a 2023 recipient of an Innovation Award by the Network of Pancreatic Donors with Diabetes.

‘Pre-conditioning’ restores immune tolerance

A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered.

Autoimmunity advance

Vanderbilt researchers have developed a high-throughput screening method to identify and characterize antigen-specific B cells — potential biomarkers for autoimmune disease and targets for new treatments.

Targeting glucagon action in diabetes

Disrupting the action of glucagon — a pancreatic hormone that works to raise blood glucose — restores functional insulin-producing cells in mouse models of type 1 diabetes and may be a promising treatment strategy.

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Pancreatic cancer clue

Inflammation synergizes with a cell’s intrinsic genetic program to promote the development of pancreatic cancer.

Team members involved in the study include, from left, Melissa Hilmes, MD, Daniel Moore, MD, PhD, Alvin Powers, MD, Jon Williams, PhD, and Jack Virostko, PhD. (photo by Jessica Kimber)

Study expands insight on shrinking pancreas in type 1 diabetes

Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) have discovered a progressive decline in pancreas volume over a one-year period in children and adolescents with newly diagnosed Type 1 diabetes.