LDL

Vitamin D impact on disease biomarkers

In a randomized controlled trial, vitamin D supplementation did not improve biomarkers for cardiovascular and metabolic disease.

Probing statin-associated diseases with genetics

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

Cholesterol

NIH grant bolsters research on heart disease, cholesterol

Thanks to major funding from the National Institutes of Health (NIH), researchers at Vanderbilt University Medical Center have made major inroads in understanding how high-density lipoprotein (HDL), commonly known as good cholesterol, in some cases may actually contribute to the development of atherosclerosis.

New tool to probe genetic mechanisms of disease

Vanderbilt Genetics Institute investigators have added a new method to the computational genetics toolbox. Their approach, described in the journal Nature Genetics, integrates vast genomics datasets to predict gene expression and facilitate discovery of genetic mechanisms underlying human diseases.

From left, Ryan Allen, PhD, MacRae Linton, MD, Kasey Vickers, PhD, Quanhu Sheng, PhD, and colleagues are working to create a new model of atherosclerosis development. (photo by Susan Urmy)

VUMC investigators receive Keck Foundation award for novel atherosclerosis research

A team of researchers has received a $1 million grant from the W.M. Keck Foundation to explore a novel model of atherosclerosis development.

Cholesterol

Obesity negates beneficial drug effects

A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.