NCI

August 5, 2014

Drug discovery clues in network map

Vanderbilt investigators have constructed a network map that could guide the development of new targeted cancer therapies.

By Bill Snyder
July 31, 2014

New target for breast cancer therapy

The protein MTBP is overexpressed in an aggressive type of breast cancer, and it regulates another protein implicated in many cancer types, suggesting that it may be a good target for new therapeutics.

By Leigh MacMillan
July 18, 2014

Neural receptor for reovirus

A newly identified receptor allows mammalian reovirus to infect neurons, shedding light on factors important for viral encephalitis.

By Leigh MacMillan
May 23, 2014

Repair protein’s DNA recognition motif

Insights into the workings of DNA damage response proteins such as SMARCAL1 could suggest new ways to improve genome integrity and prevent cancer.

By Leigh MacMillan
May 22, 2014

Cellular forces aid tumor invasion

The contractile machinery inside tumor cells increases invasive properties, suggesting it might be a good target to inhibit cancer cell spread.

By VUMC News and Communications
May 9, 2014

Bypassing DNA damage

Studies of a human polymerase that replicates DNA have provided a complete kinetic and structural framework for understanding how the enzyme accurately bypasses DNA damage.

By VUMC News and Communications
May 8, 2014

PET probe detects dying tumor cells

A novel PET imaging probe detects tumor cell death in vivo and could be useful for personalizing cancer medicine.
By Leigh MacMillan
April 25, 2014

Increased cell permeability may protect from colitis

Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.
By Leigh MacMillan
March 13, 2014

A new way to target cancer-driver Ras

Vanderbilt researchers have discovered small molecules that turn off cancerous Ras signals in a new way.
By Leigh MacMillan
February 7, 2014

New direction for treating lung cancer

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.
By Leigh MacMillan
January 23, 2014

Human and Helicobacter co-evolution

By VUMC News and Communications
January 20, 2014

Moses to receive Vanderbilt Distinguished Alumni Award

Harold “Hal” Moses, the Hortense B. the Ingram Professor of Cancer Research at Vanderbilt University, is the recipient of the 2014 Distinguished Alumni Award — the highest honor for a member of the Vanderbilt alumni community.
By VUMC News and Communications
December 18, 2013

Targeting tumor “supply lines”

A metabolic enzyme plays a crucial role in vascular development and may be a good target for cancer therapies.
By Leigh MacMillan