NIDDK

October 12, 2018

Targeting diabetic kidney disease

Pathways activated by the epidermal growth factor receptor may be attractive targets to treat diabetic kidney disease, according to new findings from Vanderbilt investigators.

By Sanjay Mishra
Insulin in vials
October 11, 2018

Insulin accelerant

It’s possible to increase the permeability of blood vessels and accelerate insulin action in muscle, Vanderbilt researchers have discovered.

By Laura Daniel
September 27, 2018

Fat tissue’s “iron sink”

Alyssa Hasty and colleagues demonstrated that immune cells called macrophages act in fat tissue to store iron and prevent iron toxicity.

By Sanjay Mishra
September 14, 2018

Diabetes drug may prevent cancer

The research suggests that metformin should be further studied clinically for the prevention of liver cancer.

By VUMC News and Communications
September 13, 2018

How microvilli form

A protein called IRTKS helps build the microvilli that form the border of cells in the intestines, explaining why the protein is a frequent target of gut pathogens.

By Sanjay Mishra
September 13, 2018

Healthy antibodies reverse diabetes

Vanderbilt researchers have discovered that IgM-type antibodies appear to play a protective role to prevent the development of type 1 diabetes — and that purified IgM antibodies can reverse the disease.

By Leigh MacMillan
September 5, 2018

Unleashing TIGER on small RNAs

Vanderbilt investigators have developed a new analytical tool to identify, quantify and analyze small RNAs.
By Leigh MacMillan
August 30, 2018

Investigators find that bile acids reduce cocaine reward

Bile acids — gut compounds that aid in the digestion of dietary fats — reduce the desire for cocaine, according to a new study by researchers at Vanderbilt and the University of Alabama at Birmingham.
By Leigh MacMillan
August 16, 2018

YAP after acute kidney injury

Activation of the signaling protein YAP may be a target for treating acute kidney injury, which affects up to 20 percent of hospitalized patients.
By Sanjay Mishra
August 16, 2018

NIDDK director lauds medical student research contributions

Griffin Rodgers, MD, director of the National Institutes of Health’s National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), was a special guest during the 10th annual NIDDK Medical Student Research Symposium held earlier this month on the Vanderbilt University campus.
By Jill Clendening
July 19, 2018

Novel insights on “leaky” gut

A protein involved in binding cells together helps maintain the integrity of the intestinal mucosa and plays a protective role in ulcerative colitis.
By Niyati Vachharajani
July 2, 2018

SMAD4 clue to colon cancer

Loss of a gene that is part of the TGF-beta signaling pathway increased inflammation in the colon and was observed in half of human colitis-associated cancers.
By Bill Snyder
July 2, 2018

Mother knows best

The first demonstration of bacterial DNA in mammalian fetal intestinal tissue suggests that the mother’s microbiome moves into the fetal intestine.
By Leigh MacMillan