NIDDK

Cholesterol

Obesity negates beneficial drug effects

A drug that improves levels of “good” cholesterol may not be beneficial for obese individuals, Vanderbilt researchers have discovered.

Low health literacy associated with early death for cardiovascular patients

Patients hospitalized with a cardiovascular event are more likely to die within one year if they have low health literacy, according to a Vanderbilt University Medical Center study released this week in Mayo Clinic Proceedings.

Team’s findings show glutamine metabolism affects T cell signaling

The cellular nutrient glutamine launches a metabolic signaling pathway that promotes the function of some immune system T cells and suppresses others, Vanderbilt researchers have discovered.

Targeting diabetic kidney disease

Pathways activated by the epidermal growth factor receptor may be attractive targets to treat diabetic kidney disease, according to new findings from Vanderbilt investigators.

Insulin in vials

Insulin accelerant

It’s possible to increase the permeability of blood vessels and accelerate insulin action in muscle, Vanderbilt researchers have discovered.

Fat tissue’s “iron sink”

Alyssa Hasty and colleagues demonstrated that immune cells called macrophages act in fat tissue to store iron and prevent iron toxicity.

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