NIDDK Archive — Page 9 of 22

Manual blood pressure monitor with a blue cuff, round pressure gauge, black inflation bulb, and attached stethoscope on a white background.
March 28, 2019

Drug interaction causes hypotension

A muscle relaxing-drug and inhibitors of the metabolic enzyme CYP1A2 interact to cause severely low blood pressure and should not be co-prescribed, Vanderbilt investigators caution.

Medical illustration of the kidneys highlighted in pink on either side of the lower spine and pelvis, shown within a translucent blue human torso.
March 14, 2019

Reprogramming cells for kidney repair

Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.

Fluorescence microscopy image showing blue-stained cell nuclei surrounded by green cell bodies and branching extensions against a black background; the cells appear separated and variably spread.
February 28, 2019

Protein loss promotes cell migration

The protein kinase STK17A plays a novel role in epithelial cells and its loss may contribute to colorectal cancer invasion and metastasis, Vanderbilt researchers report.

Super-resolution microscopy image of mouse intestine showing a curved band of white microvilli tipped with yellow cadherin; red cell nuclei appear below against a dark background.
February 14, 2019

Adhesion protein optimizes border

Matthew Tyska and colleagues have found that an adhesion protein plays a key role in building the intestinal brush border that is essential for absorbing nutrients.

January 31, 2019

New target for chronic kidney disease

Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.

white pills spilling out of a prescription bottle
January 17, 2019

Pain relievers a risk for C. diff?

A link between anti-inflammatory drugs such as ibuprofen and C. diff infection suggests caution against overusing such drugs in patients at high risk for infection.