NIDDK

April 16, 2014

Channel drug restores glucose balance

A new compound that activates potassium channels could be used to treat disorders of glucose homeostasis.

By Bill Snyder
Insulin in vials
April 10, 2014

Matrix remodeling and insulin resistance

The extracellular matrix that surrounds cells plays a role in the development of insulin resistance.

By Will Fry
Heart illustration
April 2, 2014

Development and disease in the aorta

Smooth muscle cells that line the aorta differ in development but not in the adult, a finding that has implications for understanding aortic development and disease.

By Peng Xu
February 12, 2014

Obesity sends immune cells to the brain

Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.

By Leigh MacMillan
February 7, 2014

New direction for treating lung cancer

Targeting the production of molecules that promote tumor blood vessel development offers a new path for treating lung cancer.

By Leigh MacMillan
January 29, 2014

Is healthy obesity possible?

It might be possible to generate a “metabolically healthy” state of obesity by targeting signaling pathways that improve insulin sensitivity.

By Leigh MacMillan
January 23, 2014

Human and Helicobacter co-evolution

By VUMC News and Communications
December 12, 2013

Therapeutic target for gastric cancer

A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.
By Leigh MacMillan
November 7, 2013

Neurotransmitter’s role in bone balance

Removal of the neurotransmitter norepinephrine from the space outside cells plays an important role in the regulation of bone remodeling.
By Leigh MacMillan
October 16, 2013

Relaxin combats insulin resistance

The hormone relaxin may offer a novel approach for treating diet-induced insulin resistance.
By Leigh MacMillan
September 26, 2013

Cell changes en route to stomach cancer

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.
By Leigh MacMillan
August 28, 2013

Probing intestinal immune cell roles

A new in vitro system will allow investigators to explore how immune system T cells develop specialized functions.
By Leigh MacMillan
August 26, 2013

Tumor factor spurs blood vessel growth

A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.
By Leigh MacMillan
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