NIDDK

March 1, 2013

Target for inflammatory bowel disease

The factor STAT6 appears to play a role in the pathogenesis of an inflammatory bowel disease, suggesting it may be a promising target for new treatments.

By Leigh MacMillan
February 18, 2013

Pancreas cells full of potential

Adult cells in the pancreas can return to a less mature state – and then become a different cell type, like the beta cells that secrete insulin.

By Jessica Mazerik
February 6, 2013

Linking oxygen, iron and red blood cells

The HIF oxygen-sensing pathway and its responses to low oxygen may be targeted for treatments of anemia and disorders of iron balance.

By Leigh MacMillan
January 31, 2013

Do-it-yourself repair in the kidney

The kidney can mediate its own repair through proliferation of resident immune system cells.

By Leigh MacMillan
January 21, 2013

HDL cholesterol impaired in kidney disease

HDL cholesterol is impaired in patients with chronic kidney disease – and may increase their cardiovascular disease risk.

By Leigh MacMillan
January 17, 2013

Study helps define pancreatic cancer’s cellular origins

Vanderbilt and University of California investigators have discovered the “cell of origin” for pancreatic ductal adenocarcinoma, a finding that could lead to early detection methods and new treatments.

By Leigh MacMillan
December 20, 2012

Cancer markers from archived tissue

Archived tissue samples are yielding new disease biomarkers.
By VUMC News and Communications
November 19, 2012

Bird’s eye view of gut development

A new map of the developing gut of quail offers valuable tool for studying intestinal diseases.
By VUMC News and Communications
October 23, 2012

Stomach bug alters tumor suppressor

The stomach bug Helicobacter pylori increases forms of a protein that promote tumor development, perhaps explaining how it elevates risk for gastric cancer.
By Leigh MacMillan
October 18, 2012

Setting traps to probe gene function

A new method for creating genetic mutations that can be activated at certain times or in specific tissues will enable studies to probe gene function.
By Leigh MacMillan
September 19, 2012

How ‘Jedi’ disposes of dead neurons

The protein Syk is essential for clearing away neuron “corpses” in the developing peripheral nervous system.
By Leigh MacMillan
September 11, 2012

Enzyme counters stomach acid attack

Dysfunction or loss of an “antioxidant” enzyme may lead to higher risk for esophageal cancer in patients with gastric reflux disease.
By VUMC News and Communications
August 7, 2012

Ancestry impacts smoking risk for lungs

Smoking is more detrimental to lung function in individuals with high proportions of African ancestry.
By Leigh MacMillan
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