NIGMS

July 13, 2015

Hhex on cancer

A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production.

By Henry H. Ong
June 16, 2015

A view of brain function in disease

Vanderbilt investigators report the first use of a specialized type of MRI to study the hippocampus in patients with schizophrenia.

By Leigh MacMillan
May 15, 2015

Boosting cell-based heart repair

A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells.

By Leigh MacMillan
May 6, 2015

Neurofibromin fine-tunes bone growth

The protein neurofibromin acts as a brake in a signaling pathway that is important in bone development, Vanderbilt researchers have discovered.

By Leigh MacMillan
May 1, 2015

New player in neuronal communication

Vanderbilt researchers have discovered a novel mechanism for the development of dendritic spines – sites of nerve cell communication.

By Leigh MacMillan
April 30, 2015

Team tracks how kidney responds to blood pressure meds

Changes in the kidney can limit the blood pressure-lowering effects of thiazide diuretics, a new study reports.

By Leigh MacMillan
April 2, 2015

Aging insights from budding yeast

The proteins that control entry and exit from the cell nucleus influence aging, Vanderbilt researchers have discovered.
By Leigh MacMillan
February 25, 2015

Antibiotics with anticancer potential

A series of experimental antibiotics may be a good starting point for developing new anticancer drugs.
By Leigh MacMillan
February 19, 2015

‘Stretched’ cells promote cancer

Mechanical stress appears to be a critical factor in activating normal tissue-associated fibroblasts to generate cancer-associated fibroblasts.
By Leigh MacMillan
February 9, 2015

Gene profile predicts metastasis

A specific gene expression profile represents a novel, biologically relevant “signature” for identifying colon cancers with high risk of metastatic recurrence, Vanderbilt researchers have found.
By Yan Su
February 5, 2015

Copper toxicity and Parkinson’s

A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.
By Leigh MacMillan
January 28, 2015

New clue to a devastating disease

New findings suggest a previously unrecognized role for the Sox10 transcription factor in Hirschsprung’s disease, and may lead to improved diagnostic and therapeutic approaches for this disease.
By Bill Snyder
January 26, 2015

Immune response depends on force

New studies explain how T-cell receptors use force to recognize and protect us against pathogens.
By Leigh MacMillan
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