NIGMS Archive — Page 5 of 20

Colorful 3D cutaway illustration of a spherical virus particle, showing coiled green genetic material inside a layered shell surrounded by blue and magenta surface proteins.
March 23, 2020

Cellular factor helps package flu genome

New insights on influenza genome packaging could guide strategies for interfering with the virus’s life cycle and ability to cause infection.

Close-up of a hand applying white powder with a small scoop over a photograph of a person's eye on a textured surface.
March 19, 2020

Blocking stress-induced relapse

Danny Winder and colleagues are teasing apart the actions of neurotransmitter receptors in a brain region linked to anxiety and addiction, with a goal of finding treatments for substance use disorders.

Newborn baby resting in a hospital incubator with monitoring electrodes attached to the chest, while an adult’s hand gently touches the baby’s head.
March 5, 2020

Clues to lung injury in preterm babies

Jennifer Sucre and colleagues have discovered a factor that contributes to the pathological changes of bronchopulmonary dysplasia, the most common complication of preterm birth.

Mud-covered hands scoop wet sediment from shallow, murky water beside clumps of mud.
February 25, 2020

Looking through MudPIT for protein interactions

The identification of novel protein interactions and sites of modification in proteins involved in mRNA translation adds to understanding of a process that is an important therapeutic target.

Close-up of analog electricity meters with black needles and numbered dials, labeled “KILOWATT.”
February 20, 2020

Transporter mutation alters cell energy

A disease-associated mutation in a transporter protein causes cells to increase energy production, as if they are starving, Vanderbilt researchers have discovered.

Two-panel molecular surface rendering labeled A and B. Panel A shows a large multicolored protein complex with a boxed central region and an arrow pointing to panel B. Panel B magnifies the region, with labels β-TF2 and β-TF1 above an outlined area and an arrow identifying a coiled-coil domain.
February 11, 2020

A key to calcium signaling

Erkan Karakas and colleagues used cryo-electron microscopy to determine structural details of a calcium channel protein that has numerous cell signaling roles.