A comprehensive evaluation of the metabolic pathways that support Staphylococcus aureus (“staph”) growth during invasive bone infections could offer new targets for treatment.

Manuel Ascano team validates an inhibitor of the cGAS-STING signaling pathway, which is important for cellular innate immunity against bacteria, viruses, and our own damaged DNA.

Vanderbilt researchers discover how anthrax bacterium defends itself against structural damage and resists the toxicity of the antimicrobial drug targocil.

John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules.

New findings suggest that treatments that decrease oxidative damage might help with postoperative delirium that occurs in up to 30% of cardiac surgery patients.

Dylan Burnette and colleagues have discovered that two forms of the molecular motor protein myosin have distinct roles in regulating cell shape during cell division.

A disease-associated mutation in a transporter protein impairs gut barrier function, leading to gastrointestinal disease and chronic infections.