NIGMS Archive
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April 26, 2022
Calculating risk for uterine fibroids
Vanderbilt researchers have constructed a polygenic risk score for uterine fibroids that will be useful for exploring causes of these benign tumors and identifying novel drug targets and therapies. -
February 28, 2022
Invasive strep can defy zinc toxicity
Vanderbilt researchers find that invasive Group B Streptococcus strains, a significant risk to pregnant patients and infants, can grow in presence of toxic zinc levels. -
January 19, 2022
Study identifies molecular trigger of severe injury-induced inflammatory response
Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure. -
October 21, 2021
Study links genetic variants, protein expression and human diseases
An international research team has developed a new resource that connects genetic variants and protein expression, which is expected to speed the identification of genes that cause disease — and point to novel treatment strategies. -
September 30, 2021
Fibroids and preterm birth
In a large, prospective study, Vanderbilt researchers found no association between fibroids and any clinical subtype of preterm birth, supporting a reconsideration of the impression that fibroids increase preterm birth risk. -
August 19, 2021
Expression atlas for cell regulators
Vanderbilt researchers report a comprehensive tissue-specific atlas of protein and mRNA expression for p63 and p73, members of the p53 family signaling network that is the most frequent target of mutations in human cancers. -
July 22, 2021
Researchers discover that protein switches functions to regulate DNA replication
Vanderbilt biochemists have discovered what the DNA damage response protein RADX does — and how it does it.