Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation.

Clinicians should use a structured interview in people with Alzheimer’s disease to identify pain that might be otherwise overlooked.