NIH

Cellular calcium handling in diabetes

Potassium channels in a cellular organelle regulate calcium flux and appear to play a critical role in pancreatic beta cell health.

Pediatric health conditions, their treatments and the related stress hinder the prefrontal cortex, which is the region of the brain associated with learning, memory and behavior. (istock)

Goal of new tissue-chip research is to assess efficacy of novel epilepsy drugs

An interdisciplinary team of Vanderbilt University researchers has received a two-year, $2-million federal grant to develop an “organ-on-chip” model for two genetic forms of epilepsy.

Pregnant woman holding pill pack

NSAIDs, genetics and miscarriage

A certain genetic variant, in combination with the use of anti-inflammatory drugs like aspirin and ibuprofen during early pregnancy, may protect women from miscarriage.

obesity or overweight belly

Inhibiting obesity

An enzyme in the gut – NAPE-PLD – is required for the action of signaling molecules that reduce food intake and weight gain.

Acid reflux cancer link

Blocking acid reflux-induced production of reactive oxygen compounds may be a useful strategy for preventing DNA damage and decreasing the risk of esophageal cancer.

Asian baby girl getting temperature taken

Heat a trigger for seizures

Elevated body temperature alone can increase vulnerability to fever-induced seizures, even in the absence of infection or inflammation.

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