A novel mechanism could point to new therapies for a group of inherited diseases that share pathological features.

A genetic predisposition to Parkinson’s disease makes neurons more vulnerable to the toxicity of heavy metals such as copper.

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

Patients with orthostatic intolerance – problems when standing – have cognitive changes, even when seated, compared to healthy individuals.

An overactive stress response contributes to the development of insulin resistance in obese individuals, and blocking it may be therapeutically beneficial.

A particular neuronal cell population is involved in the pathogenesis of a rare neurological disorder, Vanderbilt researchers have discovered.

Drugs developed at Vanderbilt could provide a new way to treat schizophrenia in a personalized way.