PNAS

August 3, 2017

HDAC3 role in B-cell development

The histone deacetylase HDAC3 is required for the maturation of B cells, white blood cells that produce antibodies.

By Leigh MacMillan
May 25, 2017

Study finds common brain scanning technique maps electrical activity as precisely as more invasive methods

A commonly used brain scanning technique can map electrical activity under the skull as precisely as more invasive methods that rely on probes or electrodes, researchers at Vanderbilt University Medical Center (VUMC) reported this month.

By Bill Snyder
April 14, 2017

A new mode of DNA repair

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

By Leigh MacMillan
A large audience wearing 3D glasses in a darkened movie theater.
March 23, 2017

Study takes 3-D perspective on colorectal cancer

Despite dramatic recent advances in treatment, colorectal cancer killed more than 49,000 Americans last year, according to the National Cancer Institute, making it the second most lethal malignancy after cancers of the lung and bronchus.

By Bill Snyder
September 28, 2016

Targeting norovirus “noxiousness”

New discoveries will guide efforts to develop vaccines or antiviral agents for norovirus, the most common cause of infectious diarrhea.

By Bill Snyder
hand on radio tuning knob
August 11, 2016

Team explores transcription factor’s autoimmunity role

Increasing expression of a transcription factor called KLF2 can promote immunological self-tolerance and “tune down” autoimmunity, researchers at Vanderbilt University Medical Center reported recently.

By Bill Snyder
May 13, 2016

New pain medicine from a fungus?

Collybolide – a natural product isolated from a mushroom – is a promising candidate for the development of non-addictive pain medicines.
By Sanjay Mishra
March 8, 2016

Fat hormone’s role in zebrafish

The hormone leptin regulates glucose balance, but not fat stores, in zebrafish.
By Leigh MacMillan
February 11, 2016

Slight chemical change may improve TB treatments: study

One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered.
By Leigh MacMillan
February 5, 2016

Dynamics of a drug resistance transporter

Vanderbilt investigators are exploring the shape changes in a multidrug transporter to understand the mechanisms of antibacterial resistance.
By VUMC News and Communications
January 8, 2016

Copying chromosome caps

Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports.
By Leigh MacMillan
October 29, 2015

Compound developed at VUMC may delay Huntington’s disease

A compound developed by researchers at Vanderbilt University can improve early symptoms and delay progression of Huntington’s disease in a mouse model of the neurodegenerative disorder.
By Bill Snyder
October 2, 2015

The yin and yang of COX-2

New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.
By Sanjay Mishra