Reporter Jan 8 2021

doctor checking patient's blood pressure

Mitochondrial stress and hypertension

Oxidative stress and toxic products called isolevuglandins in mitochondria play a role in endothelial dysfunction and hypertension — and getting rid of them with a special “scavenger” molecule has therapeutic potential.

Microbial RNA and rheumatoid arthritis

Small RNAs — short stretches of genetic material — from microbes may be playing a role in rheumatoid arthritis and other autoimmune diseases.

Large study finds higher burden of acute brain dysfunction for COVID-19 ICU patients

COVID-19 patients admitted to intensive care in the early months of the pandemic were subject to a significantly higher burden of delirium and coma than is typically found in patients with acute respiratory failure. Choice of sedative medications and curbs on family visitation played a role in increasing acute brain dysfunction for these patients.

VUMC mourns loss of otolaryngologist and surgeon Ries

William Russell Ries, MD, professor of Otolaryngology and Carol and John S. Odess Professor of Facial Plastic and Reconstructive Surgery in the Department of Otolaryngology at Vanderbilt University Medical Center, died Jan. 5. He was 67.

Autism theory 25 years in the making

A unifying explanation of the cause of autism and the reason for its rising prevalence has eluded scientists for decades, but a theoretical model published in the journal Medical Hypotheses describes the cause as a combination of socially valued traits, common in autism, and any number of co-occurring disabilities.

Vitamin D activation and cancer risk

Vitamin D protection against colon cancer varies according to parathyroid hormone response, particularly among women.

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