statins

The study could suggest ways to promote the transport of phospholipids and cholesterol out of macrophages, immune system cells that play key roles in all stages of atherosclerosis development.

Reminders for clinicians improve prescribing for high cholesterol

A Vanderbilt study found that automated targeted reminders for clinicians helped increase prescribing of high intensity statins for patients with various atherosclerotic cardiovascular disease diagnoses, including coronary or peripheral artery disease and ischemic stroke.

Probing statin-associated diseases with genetics

Vanderbilt researchers used genetics tools and biobanks with linked electronic health records to explore the associations between statins and noncardiovascular diseases.

Amanda Mixon, MD, MS

Statins to be studied for prevention of dementia, disability and heart disease 

Vanderbilt University Medical Center researchers are enrolling adults aged 75 and over to study whether taking atorvastatin, a drug commonly used to lower cholesterol also called Lipitor®, can help maintain health by preventing dementia, disability, and heart disease.

Records point to drug-drug interaction

Patients who take a cholesterol-lowering statin drug while taking the antibiotic daptomycin have increased risk of developing muscle weakness or a more severe form of muscle damage.

Gene study spots clues to heart risk for statin patients

A Vanderbilt-led research team has discovered genetic variations that increase the risk of heart attack even when patients are receiving a statin drug like Lipitor or Crestor to lower their blood cholesterol.

HDL and kidney injury after surgery

Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.