stem cells

August 5, 2021

Motor protein linked to intestinal cell differentiation

The motor protein MYO5B, a cause of the congenital intestinal disorder microvillus inclusion disease, does more than move cellular cargo, Vanderbilt researchers have discovered.

By Sarah E. Glass
March 25, 2019

Ten years ago, Mike Lavin was saved by a bone marrow transplant. A few days ago, he paid a surprise visit to the donor who made it possible.

“I really appreciate everything you have done. I’m here because of you.”

By Tom Wilemon
March 14, 2019

Reprogramming cells for kidney repair

Using gene transfer technologies to reprogram adult human kidney cells could lead to novel therapies for chronic kidney disease.

By Kelsey Herbers
February 28, 2018

Structure of a stem cell niche

Understanding the specialized environment where stem cells reside is important for developing stem-cell based regenerative therapies.

By Leigh MacMillan
November 17, 2016

Stem cells promote tolerance

Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.

By Leigh MacMillan
August 31, 2016

Proliferative capacity of neuroblastoma

The sphere-forming frequency of neuroblastoma cells is a measure of their proliferative capacity and could help guide treatment strategies for neuroblastoma.

By Sanjay Mishra
July 13, 2015

Hhex on cancer

A new mouse model demonstrates that the Hhex gene – which is linked to blood cancers – is critical for normal blood cell production.
By Henry H. Ong
July 10, 2015

Delivering cells for heart repair

A polymer hydrogel material developed by Vanderbilt scientists improved the delivery of stem cells for heart repair.
By Leigh MacMillan
May 15, 2015

Boosting cell-based heart repair

A metabolic change in adult stem cells makes them less “fit” for regenerative heart therapies, suggesting that strategies to prevent this response may boost the therapeutic usefulness of the cells.
By Leigh MacMillan
October 9, 2014

Long-range signaling to stem cells

The potential for long-range signaling factors – such as those identified in the current study – to regulate stem cell behaviors has implications in tumor progression and metastasis.
By Leigh MacMillan
September 16, 2014

Patient-derived stem cells shed light on pulmonary hypertension

Stem cells derived from patients with pulmonary arterial hypertension provide a unique resource for studying the molecular defects that cause the disease and testing potential therapies.
By Leigh MacMillan
September 11, 2014

Engelhardt lands stem cell transplant research grant

Up to 60 percent of patients who receive a stem cell transplant using cells from another donor will develop post-transplant diabetes mellitus, which can increase the rate of complications and death after the procedure.
By VUMC News and Communications
August 20, 2014

Study finds coronary arteries hold heart-regenerating cells

Endothelial cells residing in the coronary arteries can function as cardiac stem cells to produce new heart muscle tissue, Vanderbilt University investigators have discovered.
By Leigh MacMillan