Cancer

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June 19, 2024

Study of messenger RNA regulatory mechanism reveals cancer risk genes

The Vanderbilt study used RNA-sequencing data generated in multiple normal tissues, along with matched genotype data from the Genotype-Tissue Expression Project as well as large-scale genomic data for cancers of the breast, ovary, prostate, colorectum, lung and pancreas.

By Tom Wilemon
June 12, 2024

Obesity-cancer connection discovery suggests strategies for improving immunotherapy 

The study reported in the journal Nature provides a mechanistic explanation for the “obesity paradox” — that obesity can contribute to cancer progression but also improve response to immunotherapy.

By Leigh MacMillan
Brooke Emerling, PhD, and Raymond Blind, PhD (seated, in foreground) at a 2023 scientific symposium they organized. Standing next to Blind is Hua Ya, PhD, from the City of Hope Comprehensive Cancer Center. Behind him in the light blue shirt is Emilio Hirsch, PhD, from the University of Torino, Italy.
June 7, 2024

Discovery raises hopes for new cancer therapy

The study connected the Hippo signaling pathway to phosphoinositides, a particular type of lipid, or fat molecule, which regulates cell functions that are critical in cancer, obesity and diabetes.

By Bill Snyder
June 6, 2024

Vanderbilt-Ingram Cancer Center’s clinicians will staff the Cancer Center at Cookeville Regional Medical Center

Through this agreement Vanderbilt-Ingram Cancer Center’s medical oncologists, radiation oncologists and advanced practice nurses will be Cookeville Regional’s exclusive providers of cancer services.

By Tom Wilemon
Eunyoung Choi, PhD, and James Goldenring, MD, PhD. (photo by Erin O. Smith)
June 4, 2024

Grant funds research for therapies to prevent stomach cancer

The funds will help launch a clinical trial in the U.S. with one of the therapies and compare it with another therapy from an ongoing clinical trial in Japan.

By Tom Wilemon
Graduate student Taralynn Mack, left, pipettes a sample while Alexander Bick, MD, graduate student Hannah Poisner, and Celestine Wanjalla, MD, PhD, look on.
June 4, 2024

Research raises hope for treating potentially lethal blood condition

Roughly 1 in 10 people over age 70 will develop CHIP, an explosive, clonal growth of abnormal blood cells that increases risk of blood cancers and death from cardiovascular, lung and liver disease.

By Bill Snyder
June 3, 2024

Dedication to advancing breast reconstruction surgery for patients links Perdikis, Maxwell

Perdikis now holds the recently established G. Patrick Maxwell, M.D. Chair of the Department of Plastic Surgery at Vanderbilt University Medical Center.
By Lucie Alig
May 30, 2024

Speakers share history of hereditary cancers at scientific retreat 

Speakers at the Vanderbilt-Ingram Cancer Center 25th Annual Scientific Retreat detailed the history of hereditary cancer discoveries and gave overviews about ongoing research. 
By Tom Wilemon
May 29, 2024

Robotic pancreatectomy speeds recovery time for retired educator 

He knew he needed complicated surgery, so researching his options, he learned about the Vanderbilt surgical team led by Kamran Idrees, MD, MSCI, MMHC, Ingram Associate Professor of Cancer Research.
By Tom Wilemon
May 14, 2024

Breast cancer risk variants identified for women of African ancestry

A study led by researchers from Vanderbilt-Ingram Cancer Center sheds light on some of the genetic variants that make breast cancer more deadly for women of African ancestry and significantly reduces the disparity in knowledge for assessing their genomic risk factors.
By Tom Wilemon
May 7, 2024

Study seeks to evaluate military exposures on veterans’ lung cancer risk 

A prospective cohort of veterans including those with military toxic exposures, such as burn pits, will be screened annually with low-dose chest CT to detect lung cancer and other disease early.
By Tom Wilemon
May 2, 2024

25th Annual VICC Scientific Retreat focuses on hereditary cancers

The Vanderbilt-Ingram Cancer Center 25th Annual Scientific Retreat will focus on hereditary cancers and feature nationally and internationally renowned speakers on the subject.
By Tom Wilemon
April 25, 2024

Making a splash for cancer research

The third annual Swim Across America – Nashville was held April 21 at Ensworth Natatorium on the Ensworth School’s Frist Campus. The event raises funds for research at Vanderbilt-Ingram Cancer Center.