Cancer

August 7, 2024

Epigenetic change to DNA associated with cancer risk in ‘multi-omics’ study

The new study identifies 4,248 CpG sites associated with the risk of seven different types of cancer: breast, colorectal, renal cell, lung, ovarian, prostate and testicular germ cell cancers.

By Leigh MacMillan
(photo by Donn Jones)
July 25, 2024

Cookeville celebration

Vanderbilt-Ingram Cancer Center celebrated a ribbon cutting recently  at the Cookeville Regional Medical Center Cancer Center, where Vanderbilt-Ingram medical oncologists, radiation oncologists and advanced practice nurses are now the exclusive providers for cancer care.

By Tom Wilemon
Katrin Karbstein, PhD
July 15, 2024

Katrin Karbstein appointed co-leader of Vanderbilt’s Cancer Cell Biology Research Program

There, she will develop and implement program aims, participate in strategic decision-making in the Cancer Center, direct pilot project funding, facilitate interactions among Cancer Center members, and assist in the recruiting activities for the 42-member program with over $11.7 million in annual peer-reviewed funding.

By Marissa Shapiro
July 10, 2024

Clinical trial for rectal cancer subtype shows promise for less aggressive treatment

The findings were so promising that the clinical trial is being redesigned to investigate whether radiation treatment can also be avoided.

By Tom Wilemon
Cathy Eng, MD
June 21, 2024

International overview of colorectal cancer provides multidisciplinary perspective of clinical advances

The authors hope the report will provide insight on the importance of education, screening and awareness to all health care providers.

By Tom Wilemon
(iStock)
June 19, 2024

Study of messenger RNA regulatory mechanism reveals cancer risk genes

The Vanderbilt study used RNA-sequencing data generated in multiple normal tissues, along with matched genotype data from the Genotype-Tissue Expression Project as well as large-scale genomic data for cancers of the breast, ovary, prostate, colorectum, lung and pancreas.

By Tom Wilemon
June 12, 2024

Obesity-cancer connection discovery suggests strategies for improving immunotherapy 

The study reported in the journal Nature provides a mechanistic explanation for the “obesity paradox” — that obesity can contribute to cancer progression but also improve response to immunotherapy.
By Leigh MacMillan
June 7, 2024

Discovery raises hopes for new cancer therapy

The study connected the Hippo signaling pathway to phosphoinositides, a particular type of lipid, or fat molecule, which regulates cell functions that are critical in cancer, obesity and diabetes.
By Bill Snyder
June 6, 2024

Vanderbilt-Ingram Cancer Center’s clinicians will staff the Cancer Center at Cookeville Regional Medical Center

Through this agreement Vanderbilt-Ingram Cancer Center’s medical oncologists, radiation oncologists and advanced practice nurses will be Cookeville Regional’s exclusive providers of cancer services.
By Tom Wilemon
June 4, 2024

Grant funds research for therapies to prevent stomach cancer

The funds will help launch a clinical trial in the U.S. with one of the therapies and compare it with another therapy from an ongoing clinical trial in Japan.
By Tom Wilemon
June 4, 2024

Research raises hope for treating potentially lethal blood condition

Roughly 1 in 10 people over age 70 will develop CHIP, an explosive, clonal growth of abnormal blood cells that increases risk of blood cancers and death from cardiovascular, lung and liver disease.
By Bill Snyder
June 3, 2024

Dedication to advancing breast reconstruction surgery for patients links Perdikis, Maxwell

Perdikis now holds the recently established G. Patrick Maxwell, M.D. Chair of the Department of Plastic Surgery at Vanderbilt University Medical Center.
By Lucie Alig
May 30, 2024

Speakers share history of hereditary cancers at scientific retreat 

Speakers at the Vanderbilt-Ingram Cancer Center 25th Annual Scientific Retreat detailed the history of hereditary cancer discoveries and gave overviews about ongoing research. 
By Tom Wilemon
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