acute kidney injury (AKI)

Roy Zent, MBBCh, PhD, left, Fabian Bock, MD, PhD, and colleagues are studying the factors involved in the maintenance and integrity of the kidney collecting duct.
November 4, 2021

Harrison Society researcher discovers key regulator of kidney cell structure

New research from Vanderbilt could aid efforts to promote kidney regeneration after injury or to develop engineered organs.

By Leigh MacMillan
June 4, 2020

Protecting the injured kidney

Leslie Gewin and colleagues have upended conventional dogma about Wnt/beta-catenin signaling in the kidney, finding that it protects against chronic kidney disease rather than promoting it.

By Leigh MacMillan
Edward Siew, MD, MSCI
January 28, 2020

Protein levels in urine after acute kidney injury predict future loss of kidney function

High levels of protein in a patient’s urine after acute kidney injury is associated with increased risk of kidney disease progression, Vanderbilt researchers report.

By Kelsey Herbers
October 31, 2019

Acute kidney injury recovery time impacts future risk

Interventions that impact the timing of recovery following acute injury may improve future outcomes for patients.

By Danielle Kopke
October 3, 2019

Study: personalized decision support affects intensive care

For patients in pediatric intensive care who are at high risk for acute kidney injury (AKI), giving clinicians automated decision support during the electronic order entry process increased the rate of blood testing for AKI by 9%.

By Paul Govern
January 31, 2019

New target for chronic kidney disease

Preventing the formation of secretory structures that promote scarring in the kidney could offer new therapeutic options for a disease that affects millions of people worldwide.

By Leigh MacMillan
August 16, 2018

YAP after acute kidney injury

Activation of the signaling protein YAP may be a target for treating acute kidney injury, which affects up to 20 percent of hospitalized patients.
By Sanjay Mishra
May 24, 2018

Study finds acetaminophen helps reduce acute kidney injury risk in children following cardiac surgery

Children who underwent cardiac surgery were less likely to develop acute kidney injury if they had been treated with acetaminophen in the first 48 hours after their procedures, according to a Vanderbilt study just published in JAMA Pediatrics.
By Matt Batcheldor
March 22, 2018

Kidney disease imaging

Making multiple measurements with MRI can provide comprehensive information about the molecular and cellular changes caused by kidney injury.
By Leigh MacMillan
January 17, 2018

HDL and kidney injury after surgery

Higher concentrations of high-density lipoproteins — HDL, the “good” cholesterol — may be protective against acute kidney injury after cardiac surgery, Vanderbilt researchers have discovered.
By Jenelle Grewell
June 8, 2017

New screening model quickly spots acute kidney injury

Researchers at Vanderbilt University Medical Center (VUMC) have developed a screening tool intended to more quickly identify patients with acute kidney injury (AKI).
By VUMC News and Communications
February 23, 2016

VUMC study finds statins do not ease kidney injury following cardiac surgery

By Paul Govern
November 12, 2015

Immune system a must for kidney repair

A signaling protein that is essential for recovery from acute kidney injury works by increasing the population of tissue-repairing immune cells.
By Lorena Infante