Alzheimer’s disease

March 18, 2026

Vanderbilt Center for Cognitive Medicine enrolls first Down syndrome participant for Alzheimer’s disease study

Evan Dewey and his family travel from Atlanta to participate in the ABATE study, a clinical trial evaluating a treatment that could reduce the likelihood of Alzheimer’s disease development in individuals with Down syndrome

By Danny Bonvissuto
February 24, 2026

Study identifies medical conditions that could predict future Alzheimer’s disease

The findings could suggest ways to intervene before clinical symptoms of memory and cognitive impairment become apparent.

By Leigh MacMillan
(iStock)
January 16, 2026

Study finds so-called super agers tend to have at least two key genetic advantages

Super agers were 68% less likely to harbor the gene nobody wants,APOE-ε4, compared to individuals with AD dementia in the same 80+ age group.

By Paul Govern
(iStock)
October 9, 2025

Study finds confusion in blood tests for Alzheimer’s

Even mild levels of kidney dysfunction affected the levels of several blood-based biomarkers for Alzheimer’s disease.

By Paul Govern
Keith Cole, DPT, PhD. (photo by Donn Jones)
September 15, 2025

Keith Cole receives grant to conduct integrated research on mobility, cognition and aging

Older adults experiencing dual decline are at greater risk of developing dementia than those with changes in only one area. 

By Evan Dorian
September 9, 2025

Cheating Alzheimer’s

Most people whose brains exhibit Alzheimer’s pathology don’t have the disease; they reach the end of their lives never having exhibited cognitive impairment. A new study examines the genetics of this resilience.

By Paul Govern
July 2, 2025

Vanderbilt Memory and Alzheimer’s Center receives federal funding to support world-class research as a Center of Excellence  

The announcement of the recognition of VMAC as an NIH Center of Excellence comes nearly five years after the creation of an exploratory NIA-funded Alzheimer’s Disease Research Center.
By Evan Dorian
June 17, 2025

Brain white matter abnormalities affect cognition and impact Alzheimer’s disease development: study 

Data from more than 4,000 participants reveals link between brain structure and cognitive decline.  
By Stephanie Bryan 
May 13, 2025

Monica Santisteban awarded grant from BrightFocus Foundation’s Alzheimer’s Disease Research Program

Santisteban’s research project will investigate whether the renin angiotensin system plays an important role in the progression of pathology in Alzheimer’s disease.
May 13, 2025

Study reveals sedentary behavior is an independent risk factor for Alzheimer’s disease

Researchers found that increased sedentary behavior in aging adults was associated with worse cognition and brain shrinkage in areas related to risk for developing Alzheimer’s disease.
By Stephanie Bryan
March 17, 2025

Where are all the Alzheimer’s drugs?

A new study will use innovative methods developed at VUMC to look for drugs already approved for other uses that could potentially be repurposed to treat Alzheimer's.
By Paul Govern
February 17, 2025

Weight-loss surgery associated with reduced dementia

An observational study found that bariatric surgery was associated with 63% reduced risk of Alzheimer's disease and related dementias.
By Paul Govern
January 15, 2025

Alzheimer’s study details abnormal gene expression tied to blood vessel growth

The study sets out how gene expression that drives the formation of new blood vessels exhibits different patterns, cell by cell, in the brains of people with Alzheimer's disease.
By Paul Govern