Alzheimer’s disease

December 12, 2019

Study examines HIV drug’s potential to treat Alzheimer’s

A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer’s disease.

By Bill Snyder
December 5, 2019

Study reveals mysteries of critical brain receptor complex

Poorly functioning AMPARs have been linked to a wide range of neurological and psychiatric disorders including seizures, Alzheimer’s disease, major depression and autism spectrum disorder. Understanding how AMPARs are formed and operate is essential for the rational design of pharmacological compounds that, by tuning AMPAR activity up or down, could improve treatment of these conditions.

By Bill Snyder
October 17, 2019

Grant bolsters Schrag’s Alzheimer’s disease research

Matthew Schrag, MD, PhD, assistant professor of Neurology, has received a Paul B. Beeson Emerging Leaders Career Development Award in Aging for research into the function of a novel protein linked to Alzheimer’s disease risk.

By Holly Fletcher
October 10, 2019

Study examines pain processing in co-occurring cancer, Alzheimer’s disease

A new multisite study will examine whether co-occurring Alzheimer’s disease and stage 4 breast or prostate cancer alters pain perception, potentially leading to undertreated cancer pain.

By Kelsey Herbers
July 18, 2019

How proteins spread linked to Alzheimer’s disease sex differences

The ways certain proteins spread may help explain why the prevalence of Alzheimer’s is higher in women than in men.

By Kelsey Herbers
December 14, 2018

Using a mapping technique to reassess prior Alzheimer’s studies finds ‘powerful,’ improved reproducibility

A neurologist is using a mapping analysis in a new study to rethink where symptoms or cognitive processes should show up in the brain. The results are ‘powerful.’

By Holly Fletcher
November 8, 2018

Vitamin C protects brain from seizures

Brain ascorbate — vitamin C — is important for protecting the brain against seizures and cognitive decline in Alzheimer’s disease.
By Nora Foegeding
October 25, 2018

Probing the pathology of impaired cognition

Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.
By Bill Snyder
August 30, 2018

Study links aortic stiffness with lower cerebral blood flow

Greater aortic stiffness is related to lower cerebral blood flow, especially among individuals with increased genetic predisposition to Alzheimer’s disease, according to research from Vanderbilt University Medical Center.
By Tom Wilemon
May 7, 2018

Study provides robust evidence of sex differences with Alzheimer’s gene

The APOE gene, the strongest genetic risk factor for Alzheimer’s disease, may play a more prominent role in disease development among women than men, according to new research from the Vanderbilt Memory and Alzheimer’s Center.
By Tom Wilemon
March 27, 2018

Alzheimer’s proteins in ICU survivors

The cognitive impairment that affects patients who survive a stay in the ICU does not appear to have a similar mechanism to Alzheimer’s disease, Vanderbilt researchers have discovered.
By Meredith Jackson
January 12, 2018

BOLD view of white matter

Vanderbilt investigators have discovered that functional MRI detects neural activity in both gray and white matter in the brain, suggesting new ways to investigate diseases such as Alzheimer’s and multiple sclerosis.
By Bill Snyder
December 1, 2017

Vitamin C deficiency and mitochondrial dysfunction in Alzheimer’s disease

Recent findings suggest that vitamin C deficiency could contribute to Alzheimer’s disease, suggesting that avoiding deficiency through diet and supplementation could protect against disease onset.
By VUMC News and Communications
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