Angela Jefferson Archive — Page 2 of 2

Two women pose outdoors in front of a brick wall; the woman on the left wears an orange shirt, and the woman on the right wears a black cardigan over a patterned blouse.
July 15, 2021

Arterial stiffening linked to Alzheimer’s disease

A research team from Vanderbilt University Medical Center reports in Neurology that greater stiffening of the aorta, the main artery in the human body, is associated in older adults with increased Alzheimer’s disease (AD) pathology as reflected in a range of neurochemical indicators measured in cerebrospinal fluid.

By Paul Govern
Angela Jefferson, PhD, is the founding director of the Vanderbilt Memory and Alzheimer’s Center, VUMC’s newest freestanding institutional center.
October 1, 2020

VUMC forms center focused on Alzheimer’s and related dementias

Leaders at Vanderbilt University Medical Center have announced that the Vanderbilt Memory and Alzheimer’s Center (VMAC), currently housed in the Department of Neurology, will become a freestanding institutional center.

By Paul Govern
Stylized side-profile illustration of a human head showing a glowing, interconnected brain and nervous system in blue, purple, and pink.
August 6, 2020

Grant supports research on abnormal brain aging

With the aid of an $18.2 million, five-year grant renewal from the National Institute on Aging, the Vanderbilt Memory and Aging Project (VMAP) will advance interdisciplinary research into abnormal brain aging and cognitive decline in older adults, with continuing emphasis on the role of blood flow changes in the heart and brain.

By Paul Govern
Overlapping word cards feature “Alzheimers” prominently, surrounded by terms including “Delusion,” “Memory Loss,” “Dementia,” “Depression,” and “Irritability.”
May 7, 2020

New study examines Alzheimer’s disease images and molecular biomarkers

Alzheimer’s disease (AD) involves distinctive wasting away of certain brain regions, such that medical imaging of these regions can distinguish the disease from other subtypes of dementia.

By Paul Govern
Portrait of a smiling woman with long light-brown hair wearing a gray blazer and white shirt.
March 21, 2019

Small vessel disease MRI marker linked to worse cognitive health in older adults

Enlarged perivascular spaces, which are commonly seen on brain MRIs in older adults, have important associations with worse cognitive performance, particularly information processing speed and executive function, according to a new study that challenges historical consideration that perivascular spaces are a harmless imaging marker.

By Holly Fletcher
Multiple blue-toned sagittal MRI scans of the human brain arranged together, with white technical labels overlaid.
October 25, 2018

Probing the pathology of impaired cognition

Detecting the neuropathology underlying cognitive impairment by lead to new targeted therapies.

By Bill Snyder