Researchers identify new therapeutic target for salt-sensitive hypertension

The Vanderbilt Health team discovered that a signaling pathway called AP-1 complex links dietary sodium to immune-driven salt-sensitivity of blood pressure, which increases the risk of cardiovascular disease and death.

Clue to salt-sensitive blood pressure found

Despite the well-established link between high salt intake and cardiovascular disease and stroke, the mechanism of SSBP is poorly understood, and it remains an untreatable cardiovascular risk with no widely available diagnostic tool.

Study sheds light on the development of inflammation, high blood pressure and resulting kidney damage

Researchers discover how salt increases blood pressure

A Vanderbilt research team has discovered that activation of a certain protein complex involved in the inflammatory response in immune cells contributes to salt-sensitive hypertension.

High blood pressure genes improve heart surgery survival in children

Vanderbilt researchers have found that children with a genetic makeup that predicts high blood pressure as adults are more likely to survive congenital heart defect repair surgery.

Vanderbilt study suggests way to prevent rare lung disease

Research by Vanderbilt scientists suggests that it may be possible to prevent or even reverse pulmonary arterial hypertension, a rare, progressive disease characterized by narrowing of and high blood pressure in the small arteries of the lungs.