Daniel Claassen

September 7, 2023

Low-flow cerebrospinal fluid in Huntington’s disease: study

Vanderbilt researchers found reduced net flow of cerebrospinal fluid in Huntington’s disease, which could contribute to mutant protein retention and altered responsiveness to medications delivered via the spinal cord.

By Paul Govern
May 22, 2023

Neurofluid flow and Alzheimer’s disease

Vanderbilt researchers used novel MRI methods to noninvasively quantify measures of neurofluid circulation and found that hypertrophy of a site of cerebrospinal fluid egress may be related to amyloid-beta retention in Alzheimer’s disease.

By Leigh MacMillan
November 17, 2022

Study examines impulsiveness in Parkinson’s disease

Vanderbilt researchers are studying aspects of dopamine release and its regulation in Parkinson’s patients with and without impulsive-compulsive behaviors.

By Paul Govern
Danielle Buchanan, BS, right, and Daniel Claassen, MD, MS, are studying the relationship between clinical research coordinators principal investigators. (photo by Donn Jones)
March 8, 2021

Survey identifies factors in reducing clinical research coordinator turnover

Strong, collaborative relationships with principal investigators are a key factor of longevity in clinical research coordinator positions — an essential, but increasingly transient job in executing treatment-advancing clinical trials, Vanderbilt University Medical Center researchers found.

By Holly Fletcher
October 27, 2017

Impulsivity in Parkinson’s Disease

A noninvasive MRI technique may help predict a troubling side effect of common medications for Parkinson’s Disease and improve clinical treatment plans.

By Allyson Mallya
August 24, 2017

Huntington’s Disease Clinic lands Level 1 designation

The Vanderbilt University Medical Center (VUMC) Huntington’s Disease Clinic is one of only four in the nation to receive a Level 1 Center of Excellence designation.

By Tom Wilemon
February 26, 2015

VUMC’s Huntington’s Disease Clinic recognized

Vanderbilt University Medical Center’s Huntington’s Disease Clinic has been named a 2015 Center of Excellence by the Huntington’s Disease Society of America (HDSA).
By VUMC News and Communications
November 21, 2013

Clinic helps patients cope with Huntington’s disease

Melissa Darnall could easily look around her family reunions and pick out who had Huntington’s disease (HD). The genetic disorder had affected four of her five aunts and uncles and her father, and the balance problems and shakiness typical of HD were readily apparent in those siblings.
By VUMC News and Communications
August 1, 2013

Case study explores stroke, meningitis link

A case series by researchers at Vanderbilt University Medical Center examines three patients transferred here with ischemic stroke who later received a diagnosis of fungal meningitis attributed to tainted injections for low back pain, part of a multi-state outbreak.
By VUMC News and Communications