Daniel Moore Archives
‘Pre-conditioning’ restores immune tolerance
Sep. 16, 2021—A treatment targeting T-cell metabolism could reinvigorate immune tolerance mechanisms to combat autoimmune disease and transplant rejection, Vanderbilt researchers discovered.
Study proves standardized protocol can support reliable MRI use for multisite pancreatic research
Aug. 27, 2021—Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) at Vanderbilt University Medical Center led a multisite study which has demonstrated that, when controlled and standardized, quantitative magnetic resonance imaging (MRI) of the pancreas is highly reproducible when using different MRI hardware and software at different geographic locations.
Study expands insight on shrinking pancreas in type 1 diabetes
Apr. 25, 2019—Researchers with the Vanderbilt Diabetes Research and Training Center (DRTC) have discovered a progressive decline in pancreas volume over a one-year period in children and adolescents with newly diagnosed Type 1 diabetes.
Healthy antibodies reverse diabetes
Sep. 13, 2018—Vanderbilt researchers have discovered that IgM-type antibodies appear to play a protective role to prevent the development of type 1 diabetes — and that purified IgM antibodies can reverse the disease.
Study uses child’s own immune system against type one diabetes
Jun. 22, 2017—Eighteen-year-old Grace Long had just been accepted at the renowned United States Naval Academy, with plans to become a nuclear engineering officer. Then, she learned she had type 1 diabetes, an immediate disqualifier for military service.
Stem cells promote tolerance
Nov. 17, 2016—Blood-forming stem cells play a role in immune tolerance and acceptance of organ transplants, Vanderbilt researchers have discovered.
VUMC researchers seek to crack the code of neonatal sepsis
Jun. 2, 2016—Sepsis, an exaggerated and overwhelming inflammatory response to infection, is a major worldwide killer of babies in the first four weeks of life (neonatal period).
Tolerating a transplant
Oct. 1, 2015—A new genetic model has generated new strategies for promoting tolerance to transplants – and improving long-term transplant outcomes – in the background of autoimmune disease.
