Department of Biochemistry Archive — Page 4 of 14
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May 5, 2020
A dual-purpose metabolic switch
John York and colleagues have demonstrated that the protein Vip1 is a rare type of bifunctional enzyme: it can both synthesize and destroy key cellular signaling molecules. -
March 23, 2020
Cellular factor helps package flu genome
New insights on influenza genome packaging could guide strategies for interfering with the virus’s life cycle and ability to cause infection. -
March 12, 2020
Triple-negative breast cancer drug therapy shows promise
Researchers from Vanderbilt-Ingram Cancer Center (VICC) discovered a role for MYCN in triple-negative breast cancer (TNBC), a particularly aggressive form of the disease, and identified a potential intervention for further clinical investigation. -
March 10, 2020
Loss of ‘Jedi’ alters neuron activity
This is not the Jedi you're thinking of. This Jedi is a receptor that helps clear away dead neurons during development, and its loss changes the activity of dorsal root ganglia neurons, which could have implications for treating chronic pain. -
February 27, 2020
Breast cancer study may help predict treatment response
Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat. -
February 6, 2020
New tool probes gene regulation
Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation. -
January 10, 2020
Structural views of a C. diff toxin
D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.