The discovery that kidney cells with mutations in a certain gene are sensitive to therapies called PI3K inhibitors opens new opportunities for applying precision medicine to cancer treatment.

Biochemistry investigators at Vanderbilt have discovered a new DNA repair mechanism that prevents gene mutations during DNA replication.

Larry Marnett and colleagues have explored the role of two enzymes in metabolizing molecules associated with cell proliferation, inflammatory processes and neurological diseases.

Vanderbilt researchers propose that cellular signaling pathways are amplified by a “conveyor belt” mechanism that exchanges active and inactive enzymes.

DNA-binding “switches” represent a fundamentally new method of communication between DNA-processing enzymes, Vanderbilt researchers propose.

Five Vanderbilt University faculty members have been elected fellows of the American Association for the Advancement of Science this year.

Katherine Rothamel, a PhD student in the Department of Biochemistry at Vanderbilt University School of Medicine, has been selected as the 2017 Vanderbilt Prize Student Scholar.