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Department of Biochemistry Archives

Slight chemical change may improve TB treatments: study

Feb. 11, 2016—One small chemical change to an existing antibacterial drug results in a compound that is more effective against its target enzyme in tuberculosis, Vanderbilt researchers have discovered.

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Nobel laureate’s lecture highlights impact of science

Jan. 28, 2016—“Stay with science,” Nobel laureate Peter Agre, M.D., advised dozens of medical and graduate students who attended his lecture at Vanderbilt University Medical Center last week. “It will take you to fascinating places.”

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Faulty building blocks in DNA

Jan. 22, 2016—An enzyme that builds DNA is able to insert the wrong building blocks, which could generate mutations.

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‘Science diplomacy’ focus of Nobel laureate Agre’s Discovery Lecture

Jan. 14, 2016—Peter Agre, M.D., a Nobel laureate who advocates the use of medical science to advance international diplomacy, will deliver the next Flexner Discovery Lecture at 4 p.m. Thursday, Jan. 21, in room 208 Light Hall.

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Copying chromosome caps

Jan. 8, 2016—Telomeres – the caps on the end of chromosomes – are a source of stress for a particular protein involved in copying DNA, a new study reports.

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Study helps clarify components of DNA ‘copy machine’

Nov. 12, 2015—Vanderbilt investigators have generated a “parts list” for the molecular machinery that duplicates DNA each time a cell divides. The research has implications for cancer therapies that target components of this machinery.

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Chazin honored with international biophysics award

Oct. 22, 2015—Walter Chazin, Ph.D., director of the Vanderbilt Center for Structural Biology, is a recipient of a 2016 Fellow of the Biophysical Society award.

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Rational design of novel antifungals

Oct. 7, 2015—Structural and molecular details of an anti-fungal target's interaction with inhibitors suggest ways to design better treatments for fungal infections.

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The yin and yang of COX-2

Oct. 2, 2015—New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.

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Framework for studying cell responses

Aug. 26, 2015—Vanderbilt investigators have developed a framework for studying cellular responses that could be used to identify the agents driving a range of biological processes in health and disease.

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How the cell makes morphine

Aug. 25, 2015—Vanderbilt investigators have discovered how mammals, including humans, produce the painkiller morphine.

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Origins of neuroblastoma

Aug. 12, 2015—Vanderbilt researchers are exploring how neuroblastoma tumors begin and progress, knowledge that could provide new treatments for this pediatric cancer.

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