Vanderbilt researchers report a structure of a human metabolic enzyme bound to its substrate 17alpha-hydroxyprogesterone.

Researchers at Vanderbilt University Medical Center (VUMC) have discovered a protein that may lead to a new way to prevent resistance and improve outcomes for patients whose cancers have mutations in the tumor suppressor gene BRCA2.

New findings shed light on how enzymes that replicate DNA skip over mutations that might cause cancer and restart DNA synthesis further away.

Vanderbilt investigators have developed a new method for measuring oxidative stress in human tumors, which provides insight into cancer development.

A new protein structure may guide the development of Alzheimer's therapeutics.

Structural details of a protein that removes DNA lesions shed light on fundamental mechanisms of DNA repair.

Jennifer Pietenpol, Ph.D., Executive Vice President for Research at Vanderbilt University Medical Center (VUMC) and director of Vanderbilt-Ingram Cancer Center (VICC), has been named a Chief Scientific Advisor (CSA) for the nonprofit breast cancer organization Susan G. Komen.