Department of Biochemistry Archive — Page 5 of 15

February 27, 2020

Breast cancer study may help predict treatment response

Researchers at VUMC are reporting another advance in the understanding and treatment of triple-negative breast cancer, which is particularly aggressive and difficult to treat.

Abstract visualization of DNA sequencing data, with multicolored nucleotide letters and fluorescent waveform peaks reflected across a digital data surface.
February 6, 2020

New tool probes gene regulation

Vanderbilt biochemists got unexpected results when they used their new approach to explore the role of DNA methylation in gene regulation.

Multi-panel molecular structure diagram showing a colored pore and prepore complex (a), with wireframe views of the pore (b) and prepore (c). Scale bars indicate 93 Å, 32 Å, and 98 Å.
January 10, 2020

Structural views of a C. diff toxin

D. Borden Lacy and colleagues used cryo-electron microscopy to define the structure of a C. diff toxin, providing a framework for the design of novel therapeutics.

Stylized microscopic illustration of translucent cells, including two connected cells with visible central nuclei, floating against a blue background.
December 17, 2019

Cell fate signaling

A newly identified protein interaction that affects cell cycle regulation may be an attractive target for cancer therapy.

Portrait of F. Peter Guengerich, a smiling older man with a gray beard, wearing a dark suit, striped shirt, and red tie.
December 12, 2019

Study examines HIV drug’s potential to treat Alzheimer’s

A drug used to treat and prevent HIV/AIDS is showing promise as a potential therapy for Alzheimer’s disease.

Neil Osheroff sits in a laboratory beside shelves of labeled bottles, sample tubes, and scientific equipment.
December 12, 2019

Osheroff elected IAMSE president

Neil Osheroff, PhD, was elected president of the International Association of Medical Science Educators (IAMSE) and will serve from January 2020-December 2021.