Department of Cell and Developmental Biology

Stress granules that form in response to cellular stress help cancer cells survive and develop resistance to treatment.

Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

A trans-institutional team of researchers at Vanderbilt University Medical Center and Vanderbilt University has received an $11 million Cancer Moonshot grant to build a single-cell resolution atlas to map out the routes that benign colonic polyps take to progress to colorectal cancer, the third most common cancer among both men and women in the United States.

A protein called IRTKS helps build the microvilli that form the border of cells in the intestines, explaining why the protein is a frequent target of gut pathogens.

New findings demonstrate a previously unappreciated role of Shh signaling activity in the proliferation of CGNPs — the presumed cell-of-origin for a subset of the malignant pediatric brain tumor medulloblastoma.

Vanderbilt University’s most prestigious faculty honor for accomplishments in research, scholarship or creative expression was awarded to Kathleen Gould, PhD, during the Fall Faculty Assembly Aug. 23.

Studies in fruit flies have shed light on how the basement membrane — a sheet-like scaffold that wraps around most animal tissues — is repaired after being damaged.