Impaired neutrophils in autoimmunity

Vanderbilt researchers help answer the question of why patients with autoimmune diseases like lupus are more susceptible to bacterial infections: their neutrophils have impaired antibacterial activity.

Study identifies molecular trigger of severe injury-induced inflammatory response

Vanderbilt researchers have discovered that early inappropriate activation of the enzyme plasmin caused by severe injury is a trigger of systemic inflammatory response syndrome and resulting organ failure.

H. pylori, lipid loss and stomach cancer

H. pylori infection — a strong risk factor for stomach cancer — changes the composition of stomach lipids, which could offer new biomarkers for detecting premalignant changes, Vanderbilt researchers discovered.

Salmonella overcomes host resistance

The invading pathogen Salmonella, a common cause of food poisoning, can change its metabolism to overcome host resistance to its colonization.

Study seeks to refine head and neck cancer treatment options

Long-acting antibody combo developed at VUMC reduces COVID-19 risk and symptoms