Department of Pathology Microbiology and Immunology

Improving natural killer cancer therapy

A newly discovered mechanism that helps cancer cells avoid destruction by immune system cells may improve immunotherapies.

An Argonaute’s voyage to cancer

A genetic mutation that promotes cancer development blocks the normal sorting of a protein called “Argonaute 2.”

Immune defenses in asthma

Vanderbilt researchers show that a certain factor negatively impacts the first-line responder cells in the lungs, providing one explanation for why patients with asthma are at greater risk for invasive bacterial disease.

Zutter takes part in cancer strategy meet at White House

Vanderbilt physician/scientist Mary Zutter, M.D., Louise B. McGavock Professor of Pathology, Microbiology and Immunology and assistant vice chancellor for Integrative Diagnostics, can now add “White House guest” to her resume.

Study identifies new culprit in lung cancer development

A microRNA — a small piece of RNA involved in regulating gene expression — functions as an oncogene to drive the development of lung cancer, Vanderbilt University investigators have discovered.

Illustration of human intestinal tract

Crystal structure reveals secrets of virulent bacterium

Researchers at Vanderbilt University Medical Center have obtained the crystal structure of a toxin from the bacterium Clostridium difficile (“C. diff”) — the leading cause of hospital-acquired diarrhea in the United States.

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