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Department of Surgery Archives

Weight regain after gastric bypass

Aug. 15, 2014—Early weight regain after gastric bypass surgery does not reverse metabolic improvements, and the "hunger hormone" ghrelin might indicate who is susceptible to weight regain.

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Increased cell permeability may protect from colitis

Apr. 25, 2014—Having a “leaky” gut may protect against colitis, a paradoxical finding that alters understanding of the role of cell permeability in intestinal homeostasis and immune regulation.

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Therapeutic target for gastric cancer

Dec. 12, 2013—A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.

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Defusing ‘C. diff’ infection

Nov. 8, 2013—Clostridium difficile (“C. diff”) infection is a leading cause of hospital-associated diarrhea, and the frequency and severity of infections are on the rise. D. Borden Lacy, Ph.D., associate professor of Pathology, Microbiology and Immunology, and colleagues recently demonstrated that the C. difficile toxin, TcdB, induces rapid cell death of human colon cell lines and pig colonic...

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Cell changes en route to stomach cancer

Sep. 26, 2013—Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.

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Tumor factor spurs blood vessel growth

Aug. 26, 2013—A newly identified factor regulates blood vessel growth in colorectal tumors and could be a promising target for cancer therapies.

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