depression

COX-2 blocker could help PTSD

COX-2 inhibitors – used clinically to reduce inflammation and pain – may find new applications for treating PTSD and other stress-related psychiatric disorders like major depression.

depressed man

Depression poses heart risk for HIV patients: study

The first study to suggest that major depressive disorder (MDD) is an independent risk factor for heart failure in HIV-positive adults has been published in Circulation.

Depression Severe Nonchronic

Depression study seeks to predict treatment response

Treating depressed individuals and figuring out who will and won’t respond to antidepressants is mostly trial and error — much to the frustration of patients and the health care providers who treat them.

New view of dopamine heteromers

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

New view of transporter dynamics

New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants.

seated man in silhouette

Skin biopsy to diagnose depression?

It may be possible to use skin cells as biomarkers to diagnose and manage depression.

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