Treating depressed individuals and figuring out who will and won’t respond to antidepressants is mostly trial and error — much to the frustration of patients and the health care providers who treat them.

Although heteromeric dopamine receptors composed of both D1 and D2 subunits have been proposed to play a role in depression and schizophrenia, recent studies suggest these heteromers do not exist.

New insights to the workings of a protein that moves neurotransmitters across the nerve cell membrane could aid the design of more effective antidepressants.

It may be possible to use skin cells as biomarkers to diagnose and manage depression.

Dynamic measurements of the bacterial leucine transporter shed light on the transporters that play roles in neuropsychiatric and addiction disorders.

Depression affects more than one out of three survivors of critical illness, according to a Vanderbilt study released in The Lancet Respiratory Medicine, and the majority of patients experience their symptoms physically rather than mentally.

A new Vanderbilt University Medical Center study shows there is no evidence that the risk of suicide differs with two commonly prescribed antidepressants prescribed to children and adolescents.