Division of Epidemiology

Epigenetic change to DNA associated with cancer risk in ‘multiomics’ study

The new study identifies 4,248 CpG sites associated with the risk of seven different types of cancer: breast, colorectal, renal cell, lung, ovarian, prostate and testicular germ cell cancers.

(Canva)

Guide to a healthier, longer life: Get up and get moving

In a study of predominantly low-income and Black Americans ages 65 and older, the researchers found that those with the longest “sitting time” — more than 10 hours a day — had the highest mortality risk.

(iStock)

Unhealthy sleep linked to diabetes across several populations

Persistently unhealthy sleep, either not enough or too much, is associated with a significantly increased risk of Type 2 diabetes in a racially and economically varied adult population, an international team of researchers has reported.

Gene variant may underlie diabetes disparities: study

The study was the largest ancestry-stratified, genetic estimation of the heritability of diabetic retinopathy conducted to date and included an unprecedented number of individuals of non-Hispanic African ancestry — more than 46,000.

(iStock)

Study of messenger RNA regulatory mechanism reveals cancer risk genes

The Vanderbilt study used RNA-sequencing data generated in multiple normal tissues, along with matched genotype data from the Genotype-Tissue Expression Project as well as large-scale genomic data for cancers of the breast, ovary, prostate, colorectum, lung and pancreas.

(iStock)

NIH grant supports effort to build expertise in genetic epidemiology research in Vietnam

V2-GENE, the Vanderbilt-Vietnam Genetic Epidemiology Training Program, will develop a team of researchers and educators to lead genetic epidemiology research of noncommunicable diseases across the lifespan in Vietnam.

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