Division of Genetic Medicine and Clinical Pharmacology Archive
-
July 14, 2023
Study uses statistical and population-based methods to understand comorbidities of developmental language disorder
A recent Vanderbilt study is one of the first to use statistical and population-based methods to understand comorbidities associated with developmental language disorder at a population level. -
June 26, 2023
Magnesium deficiency and blood pressure
Dietary magnesium depletion in a mouse model activated inflammatory pathways and molecules that promote hypertension, suggesting that increased magnesium consumption may be beneficial for reducing the prevalence of hypertension. -
June 8, 2023
Targeting calcium handling in A-fib
The drug ent-verticilide reduced A-fib incidence and duration in an animal model, suggesting it may be a viable therapeutic option. -
June 5, 2023
Study discovers that tumor mutation burden predicts survival outcome
The expected course of a patient's cancer prognosis has traditionally been judged by its type, stage and microscopic aggressiveness, but patients with the same presentation can still have widely divergent outcomes. Researchers from Vanderbilt-Ingram Cancer Center have discovered that differences in tumor mutation burden are a major reason for this divergence. -
June 5, 2023
Vanderbilt mourns loss of renowned clinical pharmacologist Jackson Roberts II, MD
Jackson Roberts II, MD, an internationally known clinical pharmacologist in the Vanderbilt University School of Medicine who helped define the role of lipid peroxidation and oxidative stress in human disease, died May 31 in Nashville. He was 79. -
May 24, 2023
Researchers probe the impact of sex and gender on human health
Vanderbilt University Medical Center's Lea Davis, PhD, and longtime colleagues Ekaterina (Katya) Khramtsova, PhD, and Barbara Stranger, PhD, are among seven authors of a paper published May 11 in the journal Cell that outlines “best practices” for evaluating the impact of both sex and gender on human health. -
May 18, 2023
New view of mutations informs disease risk, treatment response
A transcontinental research effort led by scientists from Vanderbilt University Medical Center and the University of Michigan has upended some long-standing assumptions about mutations — how often they occur, what causes them and what they do.