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epilepsy Archives

VUMC implants first patient in NAUTILUS study for treatment of idiopathic generalized epilepsy

Oct. 18, 2022—A Vanderbilt patient with idiopathic generalized epilepsy is now the first to receive neuromodular stimulation of the brain to see if it can help with seizures.

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Gene tied to childhood epilepsy

Oct. 6, 2022—Data drawn from four unrelated patients with a childhood epilepsy syndrome — and from in vitro and in vivo studies — link novel variants in a GABA transporter gene to seizure activity, Vanderbilt researchers reported.

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VWCH adds epilepsy monitoring unit, onsite neurologist

Oct. 6, 2022—Vanderbilt Wilson County Hospital has added an epilepsy monitoring unit (EMU), with a neurologist onsite seeing patients in the hospital.

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Mental health screening in epilepsy

Oct. 18, 2021—Sending survey tools to epilepsy patients before their clinic appointment doubled the numbers of patients who were diagnosed and treated for depression and anxiety disorders, Vanderbilt neurologists found.

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Sudden death from deep in the brain?

Aug. 9, 2021—Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy.

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Common mechanism found for diverse brain disorders: study

Jun. 23, 2021—Researchers at Vanderbilt University Medical Center have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.

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New neurodegeneration culprit

Jun. 17, 2021—A young woman with a puzzling neurological illness and novel genetic variant pointed investigators to a role for dysregulated protein kinase D1 in neurodegeneration.

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Inflammation in genetic epilepsy

Jan. 21, 2021—Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments.

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Functional seizures associated with stroke, psychiatric disorders in electronic health records study

Jan. 7, 2021—In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.

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Single mutation causes seizure disorder

Jun. 22, 2020—A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities.

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A new anti-seizure target?

Dec. 12, 2019—Vanderbilt neurologists have identified a protein modification that could be targeted to reduce neuronal excitability in epilepsy.

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ROSA technology helps ease patient’s violent seizures

Dec. 5, 2019—In the span of a month in December 2018, Daniel Lookabaugh suffered six severe seizures, requiring hospitalization at Monroe Carell Jr. Children’s Hospital at Vanderbilt each time to have neurological care as well as intervention from Pediatric Orthopaedics to reset his jaw and shoulder.

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