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epilepsy Archives

Mental health screening in epilepsy

Oct. 18, 2021—Sending survey tools to epilepsy patients before their clinic appointment doubled the numbers of patients who were diagnosed and treated for depression and anxiety disorders, Vanderbilt neurologists found.

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Sudden death from deep in the brain?

Aug. 9, 2021—Vanderbilt neurologists found altered excitability in deep brain structures that they note may drive respiratory dysfunction and sudden death in a rare form of epilepsy.

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Common mechanism found for diverse brain disorders: study

Jun. 23, 2021—Researchers at Vanderbilt University Medical Center have identified a common mechanism underlying a spectrum of epilepsy syndromes and neurodevelopmental disorders, including autism, that are caused by variations in a gene encoding a vital transporter protein in the brain.

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New neurodegeneration culprit

Jun. 17, 2021—A young woman with a puzzling neurological illness and novel genetic variant pointed investigators to a role for dysregulated protein kinase D1 in neurodegeneration.

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Inflammation in genetic epilepsy

Jan. 21, 2021—Brain inflammation links genetic and acquired epilepsy — providing new clues about epilepsy development and pointing to potential treatments.

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Functional seizures associated with stroke, psychiatric disorders in electronic health records study

Jan. 7, 2021—In a large-scale study of electronic health records, Vanderbilt University Medical Center investigators have determined the prevalence of functional seizures and characterized comorbidities associated with them.

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Single mutation causes seizure disorder

Jun. 22, 2020—A single mutation in one gene can impair inhibitory signaling in the brain and cause multiple types of seizures and behavioral abnormalities.

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A new anti-seizure target?

Dec. 12, 2019—Vanderbilt neurologists have identified a protein modification that could be targeted to reduce neuronal excitability in epilepsy.

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ROSA technology helps ease patient’s violent seizures

Dec. 5, 2019—In the span of a month in December 2018, Daniel Lookabaugh suffered six severe seizures, requiring hospitalization at Monroe Carell Jr. Children’s Hospital at Vanderbilt each time to have neurological care as well as intervention from Pediatric Orthopaedics to reset his jaw and shoulder.

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Blueprint for treating epilepsy

Nov. 14, 2019—Structural details of a protein that is essential to normal brain function could improve treatments for epilepsy and other seizure disorders.

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VIGH study seeks to expand epilepsy care efforts in Africa

Oct. 10, 2019—The Vanderbilt Institute for Global Health (VIGH), with Aminu Kano Teaching Hospital (AKTH), will conduct a clinical trial in three cities in northern Nigeria to determine the efficacy of shifting childhood epilepsy care to epilepsy-trained community health extension workers.

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Team discovers one more piece to the autism puzzle

Oct. 3, 2019—Vanderbilt investigators have linked genetic mutations in a single receptor to epilepsy, autism and intellectual disability.

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