Epithelial Biology Center

A large audience wearing 3D glasses in a darkened movie theater.
March 23, 2017

Study takes 3-D perspective on colorectal cancer

Despite dramatic recent advances in treatment, colorectal cancer killed more than 49,000 Americans last year, according to the National Cancer Institute, making it the second most lethal malignancy after cancers of the lung and bronchus.

By Bill Snyder
October 26, 2016

Single-cell study of tumor samples

A new method for analyzing cells in fixed biopsy tissues from patients by guide personalized treatment strategies for cancer.

By Leigh MacMillan
June 23, 2016

Goldenring recognized for research mentorship efforts

James Goldenring, M.D., Ph.D., co-director of the Epithelial Biology Center at Vanderbilt University Medical Center (VUMC), has received a Research Mentor Award from the American Gastroenterology Association Institute Council for “outstanding research mentorship.”

By Bill Snyder
alarm clock
March 17, 2016

Study suggests cancer’s ‘clock’ can be rewound

Researchers at Vanderbilt University Medical Center have “turned back the clock” in a mouse model of metaplasia — precancerous stomach lesions — raising hopes that gastric cancer, a worldwide scourge that’s rising in the United States, can be prevented.

By Bill Snyder
March 3, 2016

Clinicians, researchers team to treat boy’s rare disorder

Test after test failed to reveal why Denny Majano wasn’t gaining weight or why he suffered from severe, chronic diarrhea. At 5 weeks old, instead of gaining weight as newborns should, Denny had lost a pound since birth.

By Christina Echegaray
December 14, 2015

DISSECTing cell signaling networks

Vanderbilt researchers have developed a new method to study cell signaling networks at single-cell resolution.

By Leigh MacMillan
September 3, 2015

Bad “traffic” linked to cancer

Understanding how signaling molecules are transported within and out of the cell may help to uncover the causes of certain cancers.
By VUMC News and Communications
April 17, 2014

Nutrient-absorbing surface’s assembly revealed: study

Vanderbilt University researchers have discovered how intestinal cells build the "brush border" -- a specialized surface structure that is critical for absorbing nutrients and defending against pathogens.
By Leigh MacMillan
November 8, 2013

Defusing ‘C. diff’ infection

By Leigh MacMillan
September 26, 2013

Cell changes en route to stomach cancer

Molecular characterization of pre-cancerous changes in cells lining the stomach could point to lesions with a greater risk of progression to cancer.
By Leigh MacMillan
August 15, 2013

$5.2M NIH grant bolsters colorectal cancer research

Robert Coffey Jr., M.D., Ingram Professor of Cancer Research at Vanderbilt University, has received a five-year, $5.2 million grant from the National Institutes of Health (NIH) to study the role of extracellular RNA (ex-RNA) in colorectal cancer.
By Bill Snyder
July 11, 2013

New ‘super’ microscopes sharpen cellular imaging

Two new “super-resolution” optical microscopes have put Vanderbilt University Medical Center on the cutting edge of cellular imaging, and are giving researchers their first views of the cell at the molecular level.
By Bill Snyder
June 20, 2013

Disease linked to cell traffic jams

Diseases associated with mutations and changes in expression of the protein caveolin may result from faulty trafficking of the protein to the cell surface.
By Leigh MacMillan