Huntington’s disease Archives
Low-flow cerebrospinal fluid in Huntington’s disease: study
Sep. 7, 2023—Vanderbilt researchers found reduced net flow of cerebrospinal fluid in Huntington’s disease, which could contribute to mutant protein retention and altered responsiveness to medications delivered via the spinal cord.
Early effects of Huntington disease
Jan. 6, 2023—Impairments in brain executive function happen earlier than motor symptoms in people with the gene mutation that causes Huntington disease, suggesting younger ages and cognitive symptoms be considered for any future clinical trials.
Breaking bad with Huntington’s disease
Oct. 5, 2021—Illegal activities are a significant clinical problem in individuals with Huntington’s disease, highlighting the need for improved screening measures and protocols to guide patient management.
Huntington’s Disease Clinic lands Level 1 designation
Aug. 24, 2017—The Vanderbilt University Medical Center (VUMC) Huntington’s Disease Clinic is one of only four in the nation to receive a Level 1 Center of Excellence designation.
Compound developed at VUMC may delay Huntington’s disease
Oct. 29, 2015—A compound developed by researchers at Vanderbilt University can improve early symptoms and delay progression of Huntington’s disease in a mouse model of the neurodegenerative disorder.
VUMC’s Huntington’s Disease Clinic recognized
Feb. 26, 2015—Vanderbilt University Medical Center’s Huntington’s Disease Clinic has been named a 2015 Center of Excellence by the Huntington’s Disease Society of America (HDSA).
New tools to probe manganese biology
Nov. 26, 2014—Vanderbilt researchers have developed tools to probe the role of the essential metal manganese in neurons, and which offer a started point for developing therapeutic agents for manganese-related neurological disorders.
Clinic helps patients cope with Huntington’s disease
Nov. 21, 2013—Melissa Darnall could easily look around her family reunions and pick out who had Huntington’s disease (HD). The genetic disorder had affected four of her five aunts and uncles and her father, and the balance problems and shakiness typical of HD were readily apparent in those siblings.