immunology

Nobel laureate explores genomics of immune response

In a wide-ranging lecture that moved from plants to nematode worms to human leukemia, Nobel laureate Andrew Fire, Ph.D., outlined his vision for a genomics-based understanding of how organisms respond to novel information.

Do-it-yourself repair in the kidney

The kidney can mediate its own repair through proliferation of resident immune system cells.

lungs

New therapeutic target for cold, flu viruses identified

Viruses that cause acute respiratory infections — such as human metapneumovirus (HMPV) and flu — impair a set of immune system cells that should clear the virus from the lungs.
Now, Vanderbilt University investigators have discovered the signaling pathway that disables these immune cells.

Targeting post-transplant diabetes

Targeting diabetes that develops after a stem cell transplant may help moderate graft-vs.-host disease, an adverse effect of the procedure, and improve outcomes.

antibodies

Diversity key in antibody repertoire

Antibodies to the 2009 H1N1 influenza strain reveal new insights into how antibody diversity forms and functions, with possible implications for designing flu vaccines.

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