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inflammation Archives

The yin and yang of COX-2

Oct. 2, 2015—New findings add to the understanding of how the enzyme COX-2 works, which is critical to the development of COX-2-targeted anti-inflammatory drugs.

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Vitamin C protects blood vessel lining

Sep. 4, 2015—Dietary vitamin C may maintain healthy blood vessels in patients with inflammatory diseases.

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Study explores protein’s role in inflammation-associated cancer

Jul. 23, 2015—An antioxidant protein may protect against colon cancer that develops in patients with inflammatory bowel disease, suggesting new strategies for reducing colon cancer risk in these patients.

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Does fish oil help prevent A-fib?

Jan. 9, 2015—Growing evidence suggests that fish oil, thought to directly prevent inflammation, oxidative stress and heart disease, may have limited clinical utility.

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Gene influences allergies in asthma

Nov. 24, 2014—A particular gene is associated with a specific type of inflammatory response in people with asthma – a finding that could suggest new therapeutic targets for treating asthma.

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Host sequesters zinc to control stomach bug

Nov. 21, 2014—Understanding how zinc and the host’s immune response control H. pylori’s cancer-causing potential could suggest new therapeutic strategies to reduce infection and cancer risk.

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Peptide quells “genomic storm”

Oct. 28, 2014—A cell-penetrating peptide developed at Vanderbilt blocks the signaling pathways that lead to lethal shock caused by bacterial infection.

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Dioxin, fathers and preterm birth

Sep. 18, 2014—Exposure of male mice to the pollutant dioxin causes preterm birth across multiple generations, suggesting that efforts to prevent preterm birth should include pre-conception interventions for dads.

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Anti-inflammatory protein “rheostat” sheds light on leaky blood vessels

Aug. 1, 2014—Vanderbilt researchers have discovered that the protein CRADD counteracts inflammatory injury to endothelial cells, which could assist the development of new therapies for inflammatory vascular disorders.

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Obesity sends immune cells to the brain

Feb. 12, 2014—Obesity causes peripheral immune cells to move to the brain, where they may contribute to inflammation and the pathophysiology of obesity.

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Therapeutic target for gastric cancer

Dec. 12, 2013—A protein kinase linked to inflammation and tumor development may be a good target for gastric cancer therapies.

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New target for stopping inflammation

Oct. 11, 2013—Importin alpha 5, a member of a family of proteins that “shuttle” other proteins into the nucleus, is a potential new target for drugs to treat inflammatory diseases.

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Recent Stories from VUMC News and Communications Publications

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer.  Don’t hesitate. Do it.

Momentum

Betsy Williams has firsthand advice for parents on the fence about whether their adolescent children should be vaccinated for the common human papilloma virus (HPV), which can lead to six types of cancer. Don’t hesitate. Do it.

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

Vanderbilt Medicine

Keeping pace: Nashville, once a mid-size city with a Southern small-town feel, is experiencing explosive growth.

VUMC campus

VUMC campus

Vanderbilt University School of Medicine entrance

Vanderbilt University School of Medicine entrance

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